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Valacyclovir hydrochloride

🥰Excellent
Catalog No. T1087Cas No. 124832-27-5
Alias Valaciclovir hydrochloride, Valaciclovir HCl

Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.

Valacyclovir hydrochloride

Valacyclovir hydrochloride

🥰Excellent
Purity: 100%
Catalog No. T1087Alias Valaciclovir hydrochloride, Valaciclovir HClCas No. 124832-27-5
Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.
Pack SizePriceAvailabilityQuantity
10 mg$39In Stock
25 mg$63In Stock
50 mg$77In Stock
100 mg$98In Stock
200 mg$129In Stock
500 mg$213In Stock
1 g$315In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.
Targets&IC50
HSV1:2.9 μg/mL (IC50)
In vitro
In male CD rats, Valaciclovir was absorbed orally, efficiently metabolized and rapidly distributed.
In vivo
Valaciclovir is the L-valine ester of aciclovir, the absorption of which occurs in the intestinal lumen and is converted to the L-valine ester of aciclovir.Valaciclovir inhibits the uptake of dipeptide transporter protein substrates, e.g., cephalosporin.
AliasValaciclovir hydrochloride, Valaciclovir HCl
Chemical Properties
Molecular Weight360.8
FormulaC13H20N6O4·HCl
Cas No.124832-27-5
SmilesCl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O
Relative Density.1.55g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (152.44 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7716 mL13.8581 mL27.7162 mL138.5809 mL
5 mM0.5543 mL2.7716 mL5.5432 mL27.7162 mL
10 mM0.2772 mL1.3858 mL2.7716 mL13.8581 mL
20 mM0.1386 mL0.6929 mL1.3858 mL6.9290 mL
50 mM0.0554 mL0.2772 mL0.5543 mL2.7716 mL
100 mM0.0277 mL0.1386 mL0.2772 mL1.3858 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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